Sunday, March 27, 2011

Mesothelioma Research Shows Chemical Processes Triggered By Asbestos

As an established carcinogen, asbestos poses a number of serious health risks. If there is an important factor in asbestosis, a disease associated with more aggressive than mineral pleural mesothelioma, a cancer that develops in the lining of the lungs. An Italian study conducted by the imaging work Pascolo Lorella synchrotron soft X-ray and X-ray fluorescence (XRF) microscopy to examine the chemical composition of the affected area. The study also revealed some possible ways these chemicals may dictate the body's response to foreign asbestos fibers.

Although some researchers have linked malignant mesothelioma asbestos for some time, the fibers exact cause cancer development remains unclear. The imaging techniques used in studying the boast of a depth greater than the polling techniques used previously, revealing and deeply buried in the thing, an optical or electron microscopy were found. This method provides a more complete chemical analysis of the fibers and the internal mechanisms that occur when the fibers begin to damage the lung tissue.

Health professionals believe that the body creates an envelope around a fiber made to isolate asbestos from tissues, collectively known as an "asbestos body" of researchers. It's supposed to be a protective mechanism. L experiment, which sought to distinguish between fibers and housing, as measured silicon, iron, oxygen and magnesium content in the samples. The fibers themselves tested rich in silica, the coating such as magnesium Furthermore, iron and oxygen content.

The tissue surrounding the body of asbestos has also been shown that more iron and magnesium that tissues are not affected. Then, the researchers concluded that iron can cause oxidative stress leading to cell damage, while magnesium can cause the formation of deposits around the fibers inhaled.

The study also indicates the presence of these metals in asbestos fibers may be responsible for its carcinogenicity. Crocidolite and amosite fibers - the two most carcinogenic forms of asbestos - containing up to 30 percent iron by weight. Although not yet confirmed, it was suggested that iron-rich protein as a result of asbestos fibers deposited could increase DNA damage leading to mutations in cancer.

Researchers hope to use the results of this study to clarify the role of the chemical elements in the development of mesothelioma. The XRF procedure and the information provided should promote research at the cellular level of mesothelioma, while a new understanding of the body's response to asbestos can cause the eventual development of more effective treatments.
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